학술논문
Divergent trajectories of antiviral memory after SARS-CoV-2 infection
Document Type
article
Author
Adriana Tomic; Donal T. Skelly; Ane Ogbe; Daniel O’Connor; Matthew Pace; Emily Adland; Frances Alexander; Mohammad Ali; Kirk Allott; M. Azim Ansari; Sandra Belij-Rammerstorfer; Sagida Bibi; Luke Blackwell; Anthony Brown; Helen Brown; Breeze Cavell; Elizabeth A. Clutterbuck; Thushan de Silva; David Eyre; Sheila Lumley; Amy Flaxman; James Grist; Carl-Philipp Hackstein; Rachel Halkerston; Adam C. Harding; Jennifer Hill; Tim James; Cecilia Jay; Síle A. Johnson; Barbara Kronsteiner; Yolanda Lie; Aline Linder; Stephanie Longet; Spyridoula Marinou; Philippa C. Matthews; Jack Mellors; Christos Petropoulos; Patpong Rongkard; Cynthia Sedik; Laura Silva-Reyes; Holly Smith; Lisa Stockdale; Stephen Taylor; Stephen Thomas; Timothy Tipoe; Lance Turtle; Vinicius Adriano Vieira; Terri Wrin; OPTIC Clinical Group; PITCH Study Group; C-MORE Group; Andrew J. Pollard; Teresa Lambe; Chris P. Conlon; Katie Jeffery; Simon Travis; Philip Goulder; John Frater; Alex J. Mentzer; Lizzie Stafford; Miles W. Carroll; William S. James; Paul Klenerman; Eleanor Barnes; Christina Dold; Susanna J. Dunachie
Source
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
Subject
Language
English
ISSN
2041-1723
Abstract
The engagement of immunological memory is a key component to the protective anti-SARS-CoV-2 B and T cell responses. Here the authors assess the B and T cells of a cohort of UK healthcare workers in response to infection and longitudinally track the compartment showing distinct trajectories following early priming.