학술논문

Physical Activity, Immune System, and the Microbiome in Cardiovascular Disease
Document Type
article
Source
Frontiers in Physiology, Vol 9 (2018)
Subject
atherosclerosis
inflammation
microbiome
cardiovascular disease
physical activity
Physiology
QP1-981
Language
English
ISSN
1664-042X
Abstract
Cardiovascular health is a primary research focus, as it is a leading contributor to mortality and morbidity worldwide, and is prohibitively costly for healthcare. Atherosclerosis, the main driver of cardiovascular disease, is now recognized as an inflammatory disorder. Physical activity (PA) may have a more important role in cardiovascular health than previously expected. This review overviews the contribution of PA to cardiovascular health, the inflammatory role of atherosclerosis, and the emerging evidence of the microbiome as a regulator of inflammation.