학술논문
Subclinical cardiovascular risk signs in adults with juvenile idiopathic arthritis in sustained remission
Document Type
article
Author
Inmaculada Concepción Aranda-Valera; Iván Arias de la Rosa; Rosa Roldán-Molina; María del Carmen Ábalos-Aguilera; Carmen Torres-Granados; Alejandra Patiño-Trives; María Luque-Tevar; Alejandro Ibáñez-Costa; Rocío Guzmán-Ruiz; María del Mar Malagón; Alejandro Escudero-Contreras; Chary López-Pedrera; Eduardo Collantes-Estévez; Nuria Barbarroja
Source
Pediatric Rheumatology Online Journal, Vol 18, Iss 1, Pp 1-12 (2020)
Subject
Language
English
ISSN
1546-0096
Abstract
Abstract Background Juvenile Idiopathic Arthritis (JIA) is one of the most common chronic diseases of childhood that often persists into adulthood and can result in significant long-term morbidity. As a long lasting chronic inflammatory disease, concern has been raised regarding the risk of premature development of cardiovascular disease (CVD) in JIA. This study aims to determine whether adults with JIA in clinical remission display clinical and subclinical signs of CVD risk: inflammatory mediators, adipokines, endothelial dysfunction and oxidative stress markers. Methods This is a cross-sectional study including 25 patients diagnosed with JIA according to the International League of Associations for Rheumatology criteria (ILAR 2001) and 25 age- and sex-matched controls. Remission was determined by JADAS10