학술논문
Diversity in EWAS: current state, challenges, and solutions
Document Type
article
Source
Genome Medicine, Vol 14, Iss 1, Pp 1-4 (2022)
Subject
Language
English
ISSN
1756-994X
Abstract
Abstract Here, we report a lack of diversity in epigenome-wide association studies (EWAS) and DNA methylation (DNAm) data, discuss current challenges, and propose solutions for EWAS and DNAm research in diverse populations. The strategies we propose include fostering community involvement, new data generation, and cost-effective approaches such as locus-specific analysis and ancestry variable region analysis.