학술논문

Arctigenin: pharmacology, total synthesis, and progress in structure modification
Document Type
article
Source
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 2452-2477 (2022)
Subject
Arctigenin
pharmacology
total synthesis
structure modification
Therapeutics. Pharmacology
RM1-950
Language
English
ISSN
14756366
1475-6374
1475-6366
Abstract
Arctium lappa L. is a prevalent medicinal herb and a health supplement that is commonly used in Asia. Over the last few decades, the bioactive component arctigenin has attracted the attention of researchers because of its anti-inflammatory, antioxidant, immunomodulatory, multiple sclerosis fighting, antitumor, and anti-leukemia properties. After summarising the research and literature on arctigenin, this study outlines the current status of research on pharmacological activity, total synthesis, and structural modification of arctigenin. The purpose of this study is to assist academics in obtaining a more comprehensive understanding of the research progress on arctigenin and to provide constructive suggestions for further investigation of this useful molecule.