학술논문
Immunological and biochemical response from older adults with urinary tract infection to uropathogenic Escherichia coli virulence factors
Document Type
article
Author
Source
Revista Peruana de Medicina Experimental y Salud Pública, Vol 37, Iss 3, Pp 527-31 (2020)
Subject
Language
Spanish; Castilian
ISSN
1726-4634
1726-4642
1726-4642
Abstract
Descriptive study in which 24 urine samples from older adults with urinary tract infection (UTI), from nursing homes, were evaluated; in order to identify differences in the immune and biochemical response from older adults with UTI by Escherichia coli (E. coli) to major virulence factors in the pathogenesis of UTI. Iron concentration, TNF-α, IL-1β and antioxidant capacity in urine were determined. A relation was found between, an increase in iron and red blood cell concentration in urine, and the presence of the pap GII gene found in E. coli. It is concluded that older adults, with UTIs by E. coli with the gene pap GII, have increased tissue damage.