학술논문
Identification of a potent benzoxaborole drug candidate for treating cryptosporidiosis
Document Type
article
Author
Source
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Subject
Language
English
ISSN
2041-1723
Abstract
Cryptosporidium infection can cause severe diarrhea with limited treatment options available. Here, Lunde et al. perform a drug repositioning screen with a library of benzoxaboroles and identify AN7973 as potent inhibitor of intracellular parasite development with good efficacy in murine and neonatal dairy calf disease models.