학술논문
Epigenome-wide association studies identify DNA methylation associated with kidney function
Document Type
article
Author
Audrey Y. Chu; Adrienne Tin; Pascal Schlosser; Yi-An Ko; Chengxiang Qiu; Chen Yao; Roby Joehanes; Morgan E. Grams; Liming Liang; Caroline A. Gluck; Chunyu Liu; Josef Coresh; Shih-Jen Hwang; Daniel Levy; Eric Boerwinkle; James S. Pankow; Qiong Yang; Myriam Fornage; Caroline S. Fox; Katalin Susztak; Anna Köttgen
Source
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Subject
Language
English
ISSN
2041-1723
Abstract
Genome-wide association studies of kidney function show enrichment of associated genetic variants in regulatory regions. Here, the authors perform epigenome-wide association studies of kidney function and disease, identifying 19 CpG sites significantly associated with these.