학술논문
New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk
Document Type
article
Author
Yingchang Lu; Felix R. Day; Stefan Gustafsson; Martin L. Buchkovich; Jianbo Na; Veronique Bataille; Diana L. Cousminer; Zari Dastani; Alexander W. Drong; Tõnu Esko; David M. Evans; Mario Falchi; Mary F. Feitosa; Teresa Ferreira; Åsa K. Hedman; Robin Haring; Pirro G. Hysi; Mark M. Iles; Anne E. Justice; Stavroula Kanoni; Vasiliki Lagou; Rui Li; Xin Li; Adam Locke; Chen Lu; Reedik Mägi; John R. B. Perry; Tune H. Pers; Qibin Qi; Marianna Sanna; Ellen M. Schmidt; William R. Scott; Dmitry Shungin; Alexander Teumer; Anna A. E. Vinkhuyzen; Ryan W. Walker; Harm-Jan Westra; Mingfeng Zhang; Weihua Zhang; Jing Hua Zhao; Zhihong Zhu; Uzma Afzal; Tarunveer Singh Ahluwalia; Stephan J. L. Bakker; Claire Bellis; Amélie Bonnefond; Katja Borodulin; Aron S. Buchman; Tommy Cederholm; Audrey C. Choh; Hyung Jin Choi; Joanne E. Curran; Lisette C. P. G. M. de Groot; Philip L. De Jager; Rosalie A. M. Dhonukshe-Rutten; Anke W. Enneman; Elodie Eury; Daniel S. Evans; Tom Forsen; Nele Friedrich; Frédéric Fumeron; Melissa E. Garcia; Simone Gärtner; Bok-Ghee Han; Aki S. Havulinna; Caroline Hayward; Dena Hernandez; Hans Hillege; Till Ittermann; Jack W. Kent; Ivana Kolcic; Tiina Laatikainen; Jari Lahti; Irene Mateo Leach; Christine G. Lee; Jong-Young Lee; Tian Liu; Youfang Liu; Stéphane Lobbens; Marie Loh; Leo-Pekka Lyytikäinen; Carolina Medina-Gomez; Karl Michaëlsson; Mike A. Nalls; Carrie M. Nielson; Laticia Oozageer; Laura Pascoe; Lavinia Paternoster; Ozren Polašek; Samuli Ripatti; Mark A. Sarzynski; Chan Soo Shin; Nina Smolej Narančić; Dominik Spira; Priya Srikanth; Elisabeth Steinhagen-Thiessen; Yun Ju Sung; Karin M. A. Swart; Leena Taittonen; Toshiko Tanaka; Emmi Tikkanen; Nathalie van der Velde; Natasja M. van Schoor; Niek Verweij; Alan F. Wright; Lei Yu; Joseph M. Zmuda; Niina Eklund; Terrence Forrester; Niels Grarup; Anne U. Jackson; Kati Kristiansson; Teemu Kuulasmaa; Johanna Kuusisto; Peter Lichtner; Jian'an Luan; Anubha Mahajan; Satu Männistö; Cameron D. Palmer; Janina S. Ried; Robert A. Scott; Alena Stancáková; Peter J. Wagner; Ayse Demirkan; Angela Döring; Vilmundur Gudnason; Douglas P. Kiel; Brigitte Kühnel; Massimo Mangino; Barbara Mcknight; Cristina Menni; Jeffrey R. O'Connell; Ben A. Oostra; Alan R. Shuldiner; Kijoung Song; Liesbeth Vandenput; Cornelia M. van Duijn; Peter Vollenweider; Charles C. White; Michael Boehnke; Yvonne Boettcher; Richard S. Cooper; Nita G. Forouhi; Christian Gieger; Harald Grallert; Aroon Hingorani; Torben Jørgensen; Pekka Jousilahti; Mika Kivimaki; Meena Kumari; Markku Laakso; Claudia Langenberg; Allan Linneberg; Amy Luke; Colin A. Mckenzie; Aarno Palotie; Oluf Pedersen; Annette Peters; Konstantin Strauch; Bamidele O. Tayo; Nicholas J. Wareham; David A. Bennett; Lars Bertram; John Blangero; Matthias Blüher; Claude Bouchard; Harry Campbell; Nam H. Cho; Steven R. Cummings; Stefan A. Czerwinski; Ilja Demuth; Rahel Eckardt; Johan G. Eriksson; Luigi Ferrucci; Oscar H. Franco; Philippe Froguel; Ron T. Gansevoort; Torben Hansen; Tamara B. Harris; Nicholas Hastie; Markku Heliövaara; Albert Hofman; Joanne M. Jordan; Antti Jula; Mika Kähönen; Eero Kajantie; Paul B. Knekt; Seppo Koskinen; Peter Kovacs; Terho Lehtimäki; Lars Lind; Yongmei Liu; Eric S. Orwoll; Clive Osmond; Markus Perola; Louis Pérusse; Olli T. Raitakari; Tuomo Rankinen; D. C. Rao; Treva K. Rice; Fernando Rivadeneira; Igor Rudan; Veikko Salomaa; Thorkild I. A. Sørensen; Michael Stumvoll; Anke Tönjes; Bradford Towne; Gregory J. Tranah; Angelo Tremblay; André G. Uitterlinden; Pim van der Harst; Erkki Vartiainen; Jorma S. Viikari; Veronique Vitart; Marie-Claude Vohl; Henry Völzke; Mark Walker; Henri Wallaschofski; Sarah Wild; James F. Wilson; Loïc Yengo; D. Timothy Bishop; Ingrid B. Borecki; John C. Chambers; L. Adrienne Cupples; Abbas Dehghan; Panos Deloukas; Ghazaleh Fatemifar; Caroline Fox; Terrence S. Furey; Lude Franke; Jiali Han; David J. Hunter; Juha Karjalainen; Fredrik Karpe; Robert C. Kaplan; Jaspal S. Kooner; Mark I. McCarthy; Joanne M. Murabito; Andrew P. Morris; Julia A. N. Bishop; Kari E. North; Claes Ohlsson; Ken K. Ong; Inga Prokopenko; J. Brent Richards; Eric E. Schadt; Tim D. Spector; Elisabeth Widén; Cristen J. Willer; Jian Yang; Erik Ingelsson; Karen L. Mohlke; Joel N. Hirschhorn; John Andrew Pospisilik; M. Carola Zillikens; Cecilia Lindgren; Tuomas Oskari Kilpeläinen; Ruth J. F. Loos
Source
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
Subject
Language
English
ISSN
2041-1723
Abstract
A genome-wide association meta-analysis study here shows novel genetic loci to be associated to body fat percentage, and describes cross-phenotype association that further demonstrate a close relationship between adiposity and cardiovascular disease risk.