학술논문
DMTs and Covid‐19 severity in MS: a pooled analysis from Italy and France
Document Type
article
Author
Maria Pia Sormani; Marco Salvetti; Pierre Labauge; Irene Schiavetti; Helene Zephir; Luca Carmisciano; Caroline Bensa; Nicola De Rossi; Jean Pelletier; Cinzia Cordioli; Sandra Vukusic; Lucia Moiola; Philippe Kerschen; Marta Radaelli; Marie Théaudin; Paolo Immovilli; Olivier Casez; Marco Capobianco; Jonathan Ciron; Maria Trojano; Bruno Stankoff; Alain Créange; Gioacchino Tedeschi; Pierre Clavelou; Giancarlo Comi; Eric Thouvenot; Mario Alberto Battaglia; Thibault Moreau; Francesco Patti; Jérôme De Sèze; Celine Louapre; the Musc‐; the Covisep study groups
Source
Annals of Clinical and Translational Neurology, Vol 8, Iss 8, Pp 1738-1744 (2021)
Subject
Language
English
ISSN
2328-9503
Abstract
Abstract We evaluated the effect of DMTs on Covid‐19 severity in patients with MS, with a pooled‐analysis of two large cohorts from Italy and France. The association of baseline characteristics and DMTs with Covid‐19 severity was assessed by multivariate ordinal‐logistic models and pooled by a fixed‐effect meta‐analysis. 1066 patients with MS from Italy and 721 from France were included. In the multivariate model, anti‐CD20 therapies were significantly associated (OR = 2.05, 95%CI = 1.39–3.02, p