학술논문

More of less: Novel multi-ome profiling of single human neurons
Document Type
article
Source
Cell Genomics, Vol 2, Iss 3, Pp 100110- (2022)
Subject
Genetics
QH426-470
Internal medicine
RC31-1245
Language
English
ISSN
2666-979X
Abstract
Epigenetic modifications to DNA and chromatin interact to influence gene expression and cellular phenotypes, but defining these omics layers in complex tissues is a daunting task. In this issue of Cell Genomics, Luo et al. describe a novel single-cell multi-omic method, simultaneously profiling transcriptome, DNA methylome, and chromatin accessibility, to shed light on human neurons.