학술논문

Building an integrated serosurveillance platform to inform public health interventions: Insights from an experts' meeting on serum biomarkers.
Document Type
article
Source
PLoS Neglected Tropical Diseases, Vol 16, Iss 10, p e0010657 (2022)
Subject
Arctic medicine. Tropical medicine
RC955-962
Public aspects of medicine
RA1-1270
Language
English
ISSN
1935-2727
1935-2735
Abstract
The use of biomarkers to measure immune responses in serum is crucial for understanding population-level exposure and susceptibility to human pathogens. Advances in sample collection, multiplex testing, and computational modeling are transforming serosurveillance into a powerful tool for public health program design and response to infectious threats. In July 2018, 70 scientists from 16 countries met to perform a landscape analysis of approaches that support an integrated serosurveillance platform, including the consideration of issues for successful implementation. Here, we summarize the group's insights and proposed roadmap for implementation, including objectives, technical requirements, ethical issues, logistical considerations, and monitoring and evaluation.