학술논문
Short term outcomes of extremely low birth weight infants from a multicenter cohort study in Guangdong of China
Document Type
article
Author
Chun-Hong Jia; Zhou-Shan Feng; Xiao-Jun Lin; Qi-Liang Cui; Sha-Sha Han; Ya Jin; Guo-Sheng Liu; Chuan-Zhong Yang; Xiao-Tong Ye; Yi-Heng Dai; Wei-Yi Liang; Xiu-Zhen Ye; Jing Mo; Lu Ding; Ben-Qing Wu; Hong-Xiang Chen; Chi-Wang Li; Zhe Zhang; Xiao Rong; Wei-Min Huang; Wei Shen; Bing-Yan Yang; Jun-Feng Lv; Le-Ying Huo; Hui-Wen Huang; Hong-Ping Rao; Wen-Kang Yan; Yong Yang; Xue-Jun Ren; Dong Liu; Fang-Fang Wang; Shi-Guang Diao; Xiao-Yan Liu; Chu-Ming You; Qiong Meng; Bin Wang; Li-Juan Zhang; Yu-Ge Huang; Dang Ao; Wei-Zhong Li; Jie-Ling Chen; Yan-Ling Chen; Wei Li; Zhi-Feng Chen; Yue-Qin Ding; Xiao-Yu Li; Yue-Fang Huang; Ni-Yang Lin; Yang-Fan Cai; Zhong-He Wan; Yi Ban; Bo Bai; Guang-Hong Li; Yue-Xiu Yan; Fan Wu
Source
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Subject
Language
English
ISSN
2045-2322
Abstract
Abstract With the increase in extremely low birth weight (ELBW) infants, their outcome attracted worldwide attention. However, in China, the related studies are rare. The hospitalized records of ELBW infants discharged from twenty-six neonatal intensive care units in Guangdong Province of China during 2008–2017 were analyzed. A total of 2575 ELBW infants were enrolled and the overall survival rate was 55.11%. From 2008 to 2017, the number of ELBW infants increased rapidly from 91 to 466, and the survival rate improved steadily from 41.76% to 62.02%. Increased survival is closely related to birth weight (BW), regional economic development, and specialized hospital. The incidence of complications was neonatal respiratory distress syndrome (85.2%), oxygen dependency at 28 days (63.7%), retinopathy of prematurity (39.3%), intraventricular hemorrhage (29.4%), necrotizing enterocolitis (12.0%), and periventricular leukomalacia (8.0%). Among the 1156 nonsurvivors, 90.0% of infants died during the neonatal period (≤ 28 days). A total of 768 ELBW infants died after treatment withdrawal, for reasons of economic and/or poor outcome. The number of ELBW infants is increasing in Guangdong Province of China, and the overall survival rate is improving steadily.