학술논문
Rasmussen syndrome in a tropical environment: a study of six (6) observations
Document Type
article
Author
Carlos Othon Guelngar; Touré Mohamed Lamine; Barry Mamadou Ciré; Diakité Mamady; Konaté Mahadi; Djibo Hamani Bachir Abdoul; Sakadi Foksouna; Djibo Hassane Fatimata; Camara Naby; Kassa Dago François; Bah Fatimatou Korka; Camara Doussou; Millimono Victorine; Condé Salematou; Sakho Aminata; Diallo Mohamed Tafsir; Barry Souleymane Djigué; Diallo Mamadou Saliou; Soumah Fodé Mohamed; Sanni Yaya Aminou; Douna Granga Daouya; Rafkat Said Abdallah; Konaté Mamady; Diallo Souleymane Mbara; Cissé Fodé Abass; Cissé Amara
Source
The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, Vol 57, Iss 1, Pp 1-8 (2021)
Subject
Language
English
ISSN
1687-8329
Abstract
Abstract Background In sub-Saharan Africa, encephalitis of various etiologies is a major public health problem and Rasmussen syndrome is rarely diagnosed due to under-medicalization. The objective of this study is to describe the clinical and neuroradiological forms, especially since this affection is little known in sub-Saharan Africa as evidenced by the scarcity of publications. Results A retrospective, descriptive and analytical study of six (6) cases of Rasmussen syndrome, shows that it is an unrecognized disease in Africa. Men were more represented with a frequency of 67% with a young age. The clinical picture dominated by 100% seizures, mental deterioration and hemiparesis. The etiology is still questionable, probably autoimmune in our study. Conclusion Rasmussen syndrome accounts for 3% in 219 patients hospitalized for epileptic conditions. This study shows a clinical profile dominated by recurrent epileptic seizures refractory to the drugs Phenobarbital, Valproic Acid and Carbamazepine, the only antiepileptics available in the country. These results are valid for therapeutic and prognostic discussion.