학술논문
Mechanism of ribosome shutdown by RsfS in Staphylococcus aureus revealed by integrative structural biology approach
Document Type
article
Author
Source
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Subject
Language
English
ISSN
2041-1723
Abstract
Upon transition to stationary phase or upon stress, bacteria limit protein synthesis through small inhibitory proteins that bind the ribosome. Here the authors decipher the interaction mode of the bacterial ribosome silencing factor (RsfS) at atomic details to provide an in depth view of how it shutdowns ribosomes.