학술논문

Vagal determinants of exercise capacity
Document Type
article
Source
Nature Communications, Vol 8, Iss 1, Pp 1-7 (2017)
Subject
Science
Language
English
ISSN
2041-1723
Abstract
Demonstrating a causal relationship between cardiac vagal tone and exercise capacity has been previously limited by methodological constraints. Using genetic targeting, silencing and optogenetic recruitment of vagal motor neuron activity in rodents, Machhadaet al. provide direct evidence that vagal drive determines the ability to exercise.