학술논문
Neutralization capacity of antibodies elicited through homologous or heterologous infection or vaccination against SARS-CoV-2 VOCs
Document Type
article
Author
Meriem Bekliz; Kenneth Adea; Pauline Vetter; Christiane S. Eberhardt; Krisztina Hosszu-Fellous; Diem-Lan Vu; Olha Puhach; Manel Essaidi-Laziosi; Sophie Waldvogel-Abramowski; Caroline Stephan; Arnaud G. L’Huillier; Claire-Anne Siegrist; Arnaud M. Didierlaurent; Laurent Kaiser; Benjamin Meyer; Isabella Eckerle
Source
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
Subject
Language
English
ISSN
2041-1723
Abstract
Emerging SARS-CoV-2 variants raise concerns on protective immunity. Here the authors show that convalescent sera from people infected with Alpha, Beta, Gamma or Delta show a significant drop of Omicron-BA.1 neutralization and that vaccine-breakthrough infections with Omicron-BA.1 or Delta result in robust neutralization for both Delta and Omicron-BA.1.