학술논문

Disrupting upstream translation in mRNAs is associated with human disease
Document Type
article
Source
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Subject
Science
Language
English
ISSN
2041-1723
Abstract
The significance of translated upstream open reading frames is not well known. Here, the authors investigate genetic variants in these regions, finding that they are under high evolutionary constraint and may contribute to disease.