학술논문
Incidence and time trends of childhood hematological neoplasms: a 36-year population-based study in the southern European context, 1983–2018
Document Type
article
Author
Jan Trallero; Arantza Sanvisens; Fernando Almela Vich; Noura Jeghalef El Karoni; Isabel Saez Lloret; Cristina Díaz-del-Campo; Ana Isabel Marcos-Navarro; Amaia Aizpurua Atxega; Patricia Sancho Uriarte; Marta De-la-Cruz Ortega; María José Sánchez; Josefina Perucha; Paula Franch; María Dolores Chirlaque; Marcela Guevara; Alberto Ameijide; Jaume Galceran; Cristina Ramírez; Marta Rodríguez Camblor; Maria Araceli Alemán; Pilar Gutiérrez; Rafael Marcos-Gragera; REDECAN
Source
Frontiers in Oncology, Vol 13 (2023)
Subject
Language
English
ISSN
2234-943X
Abstract
BackgroundHematological neoplasms (HNs) are the first and most common childhood cancers globally. Currently, there is a lack of updated population-based data on the incidence of these cancers in the Spanish pediatric population. This study aimed to describe the incidence and incidence trends of HNs in children (0–14 years) in Spain using data from the Spanish Network of Cancer Registries and to compare the results with other southern European countries.MethodsData were extracted from 15 Spanish population-based cancer registries between 1983 and 2018. Cases were coded according to the International Classification of Diseases for Oncology, third edition, first revision, and grouped according to the International Classification of Childhood Cancer, third edition. Crude rates (CRs), age-specific rates, and age-standardized incidence rates using the 2013 European population (ASRE) were calculated and expressed as cases per 1,000,000 child-years. Incidence trends and annual percentage changes (APCs) were estimated.ResultsA total of 4,747 HNs were recorded (59.5% boys). Age distribution [n (%)] was as follows: