학술논문
Proteome and phosphoproteome signatures of recurrence for HPV+ head and neck squamous cell carcinoma
Document Type
article
Author
Source
Communications Medicine, Vol 2, Iss 1, Pp 1-15 (2022)
Subject
Language
English
ISSN
2730-664X
Abstract
Kaneko et al. compare the proteome and phosphoproteome of primary HPV + oropharyngeal squamous cell cancers with tumours that recurred following chemotherapy/radiation. The authors identify signatures of fibrosis, matrix remodeling, and epithelial-mesenchymal transition and reprogrammed cytoskeletal signalling in recurrent tumours.