학술논문
Interdisciplinary Collaboration on Real World Data to Close the Knowledge Gap: A Reflection on 'De Sutter et al. Predicting Volume of Distribution in Neonates: Performance of Physiologically Based Pharmacokinetic Modelling'
Document Type
article
Author
Source
Pharmaceutics, Vol 16, Iss 1, p 128 (2024)
Subject
Language
English
ISSN
1999-4923
Abstract
This commentary further reflects on the paper of De Sutter et al. on predicting volume of distribution in neonates, and the performance of physiologically based pharmacokinetic models We hereby stressed the add on value to collaborate on real world data to further close this knowledge gap. We illustrated this by weight distribution characteristics in breastfed (physiology) and in asphyxiated (pathophysiology), with additional reflection on their kidney and liver function.