학술논문

Association between lower body temperature and increased tau pathology in cognitively normal older adults
Document Type
article
Source
Neurobiology of Disease, Vol 171, Iss , Pp 105748- (2022)
Subject
Tau
Phosphorylation
Body temperature
Aging
Alzheimer's disease
Neurofibrillary tangle
Neurosciences. Biological psychiatry. Neuropsychiatry
RC321-571
Language
English
ISSN
1095-953X
Abstract
Background: Preclinical studies suggest body temperature (Tb) and consequently brain temperature has the potential to bidirectionally interact with tau pathology in Alzheimer's Disease (AD). Tau phosphorylation is substantially increased by a small (