학술논문
Multi-omics signatures of the human early life exposome
Document Type
article
Author
Léa Maitre; Mariona Bustamante; Carles Hernández-Ferrer; Denise Thiel; Chung-Ho E. Lau; Alexandros P. Siskos; Marta Vives-Usano; Carlos Ruiz-Arenas; Dolors Pelegrí-Sisó; Oliver Robinson; Dan Mason; John Wright; Solène Cadiou; Rémy Slama; Barbara Heude; Maribel Casas; Jordi Sunyer; Eleni Z. Papadopoulou; Kristine B. Gutzkow; Sandra Andrusaityte; Regina Grazuleviciene; Marina Vafeiadi; Leda Chatzi; Amrit K. Sakhi; Cathrine Thomsen; Ibon Tamayo; Mark Nieuwenhuijsen; Jose Urquiza; Eva Borràs; Eduard Sabidó; Inés Quintela; Ángel Carracedo; Xavier Estivill; Muireann Coen; Juan R. González; Hector C. Keun; Martine Vrijheid
Source
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Subject
Language
English
ISSN
2041-1723
Abstract
Environmental exposures in early life can have lasting health effects, but the molecular mechanisms are not well understood. Here, the authors discover >1000 associations between exposure factors and child multi-omics profiles, revealing signatures for diet, toxic chemical compounds, essential trace elements, and weather conditions.