학술논문
The obesity paradox in early and advanced HER2 positive breast cancer: pooled analysis of clinical trial data
Document Type
article
Author
Source
npj Breast Cancer, Vol 7, Iss 1, Pp 1-6 (2021)
Subject
Language
English
ISSN
2374-4677
Abstract
Abstract While many studies have evaluated the relationship between BMI and breast cancer outcomes, it is unclear whether this relationship is consistent between early breast cancer (BC) and advanced BC. The study included 5099 patients with HER2 positive early BC (EBC) and 3496 with HER2 positive advanced BC (ABC). In the EBC cohort, higher BMI was associated with worse overall survival (OS) (HR [95% CI]: overweight = 1.30 [1.13–1.51]; obese = 1.37 [1.14–1.64], P =