학술논문

Basal ganglia engagement during REM sleep movements in Parkinson’s disease
Document Type
article
Source
npj Parkinson's Disease, Vol 8, Iss 1, Pp 1-6 (2022)
Subject
Neurology. Diseases of the nervous system
RC346-429
Language
English
ISSN
2373-8057
Abstract
Abstract To elucidate the role of the basal ganglia during REM sleep movements in Parkinson’s disease (PD) we recorded pallidal neural activity from four PD patients. Unlike desynchronization commonly observed during wakeful movements, beta oscillations (13–35 Hz) synchronized during REM sleep movements; furthermore, high-frequency oscillations (150–350 Hz) synchronized during movement irrespective of sleep-wake states. Our results demonstrate differential engagement of the basal ganglia during REM sleep and awake movements.