학술논문

Changes in sick notes associated with COVID-19 from 2020 to 2022: a cohort study in 24 million primary care patients in OpenSAFELY-TPP
Document Type
article
Author
Andrew SteptoeJohn MacleodDaniel McCartneyAziz SheikhAnnie HerbertBen GoldacreDavid EvansLouise JonesSam HarperMichael GreenNicholas TimpsonJohn WrightLiam SmeethLaurie A TomlinsonSinead BrophyKate TillingAndy GibsonPaola ZaninottoStefan NeubauerYinghui WeiBetty RamanChloe ParkAlun HughesJonathan SterneElena LukaschukStefan PiechnikAngela WoodMark GreenAgnieszka LemanskaKrishnan BhaskaranKathryn WillanElsie HorneHannah WoodwardIan DouglasAndrew WongAndy BoydHarriet ForbesSinéad LanganNishi ChaturvediTom PalmerKathryn MansfieldRachel DenholmEmily HerrettKevin WangBo HouFelix GreavesLaura SheardPraveetha PatalayKishan PatelJessica MorleyBang ZhengCharlotte BoothSpiros DenaxasBrian MacKennaRuth E CostelloJonathan KennedyWilliam HulmeMichael ParkerGeneviève CezardSyed A ShahAmir MehrkarPeter InglesbyJonathan CockburnLaurie TomlinsonJohn ParryFrank HesterEoin McElroyAmelia GreenGillian SantorelliAlisia CarnemollaRichard ShawSamantha IpVenexia WalkerEmma L TurnerRichard ThomasRebecca RheadArchie CampbellEllen ThompsonRuth BowyerJane MaddockHelen CurtisAlex WalkerOlivia HamiltonRosie McEachanEllena BadrickStephen SmithRichard DobsonStela McLachlanVanessa FerreiraVittal KatikireddiScott WalkerLucy TeeceSimon DavyJohn TazareBettina MoltrechtTheocharis KromydasGiorgio Di GessaGareth GriffithViyaasan MahalingasivamElizabeth TunnicliffeGeorge HickmanTom WardRebecca M SmithSam ParsonsCallum StewartAmos FolarinDaniel KopaskerClaire StevesLouis FisherSebastian C J BaconLisa HopcroftRobin Y ParkJon MasseyIain DillinghamSteven MaudeWels JacquesLinda NabChristopher BatesMilan WiedemannRuth MitchellChao FangFatima AlmaghrabiJingmin ZhuLucy BridgesKurt TaylorColm AndrewsJean StaffordNathan CheethamSebastian CJ BaconAlicja RapalaRobin FlaigAndrea L SchafferBenjamin FC Butler-ColeLiam Hart Ben GoldacreThomas O’DwyerDylan WilliamsAnika KnueppelKatharine M EvansSamantha BermanMatthew CraneRebecca WhitehornJacqui OakleyDiane FosterKirsteen C CampbellAlex KwongAna Goncalves SoaresRenin TomsLizzie HuntleyLaura FoxRochelle KnightNorthstone KateKanagaratnam ArunTeri NorthMarwa AL ArabJose IC CoronadoArun S KarthikeyanPloubidis GeorgeBozena WielgoszewskaCharis Bridger-StaatzPaz GarciaMaxim FreydinAmy RobertsAlex Walker Ben GoldacreJess MorleyAnoop Shah Richard SilverwoodThomas CowlingKate MansfieldTiffany YangTom BoltonAlexia SampriElena RafetiRobert WillansFiona GlenSteve SharpLee Hamill HowesLidia NigrelliFintan McArdleChelsea BeckfordYatharth RanjanJd CarpentieriSarah BazJohn KellasLaura C SaundersJames M WildPeter JezzardZeena-Britt SandersLucy FinniganMilla KibbleFrancisco Perez-RecheDominik PiehlmaierEdward Parker
Source
BMJ Open, Vol 14, Iss 7 (2024)
Subject
Medicine
Language
English
ISSN
2044-6055
Abstract
Objectives Long-term sickness absence from employment has negative consequences for the economy and can lead to widened health inequalities. Sick notes (also called ‘fit notes’) are issued by general practitioners when a person cannot work for health reasons for more than 7 days. We quantified the sick note rate in people with evidence of COVID-19 in 2020, 2021 and 2022, as an indication of the burden for people recovering from COVID-19.Design Cohort study.Setting With National Health Service (NHS) England approval, we used routine clinical data (primary care, hospital and COVID-19 testing records) within the OpenSAFELY-TPP database.Participants People 18–64 years with a recorded positive test or diagnosis of COVID-19 in 2020 (n=365 421), 2021 (n=1 206 555) or 2022 (n=1 321 313); general population matched in age, sex and region in 2019 (n=3 140 326), 2020 (n=3 439 534), 2021 (n=4 571 469) and 2022 (n=4 818 870); people hospitalised with pneumonia in 2019 (n=29 673).Primary outcome measure Receipt of a sick note in primary care.Results Among people with a positive SARS-CoV-2 test or COVID-19 diagnosis, the sick note rate was 4.88 per 100 person-months (95% CI 4.83 to 4.93) in 2020, 2.66 (95% CI 2.64 to 2.67) in 2021 and 1.73 (95% CI 1.72 to 1.73) in 2022. Compared with the age, sex and region-matched general population, the adjusted HR for receipt of a sick note over the entire follow-up period (up to 10 months) was 4.07 (95% CI 4.02 to 4.12) in 2020 decreasing to 1.57 (95% CI 1.56 to 1.58) in 2022. The HR was highest in the first 30 days postdiagnosis in all years. Among people hospitalised with COVID-19, after adjustment, the sick note rate was lower than in people hospitalised with pneumonia.Conclusions Given the under-recording of postacute COVID-19-related symptoms, these findings contribute a valuable perspective on the long-term effects of COVID-19. Despite likely underestimation of the sick note rate, sick notes were issued more frequently to people with COVID-19 compared with those without, even in an era when most people are vaccinated. Most sick notes occurred in the first 30 days postdiagnosis, but the increased risk several months postdiagnosis may provide further evidence of the long-term impact.