학술논문
Differential response to intravitreal dexamethasone implant in naïve and previously treated diabetic macular edema eyes
Document Type
article
Author
Javier Zarranz-Ventura; Barbara Romero-Núñez; Carolina Bernal-Morales; Daniel Velazquez-Villoria; Anna Sala-Puigdollers; Marc Figueras-Roca; Sergio Copete; Laura Distefano; Anna Boixadera; Jose García-Arumi; Alfredo Adan; on behalf of the Hospital Clínic - Hospital Vall de Hebron Intravitreal Dexamethasone Implant study group
Source
BMC Ophthalmology, Vol 20, Iss 1, Pp 1-12 (2020)
Subject
Language
English
ISSN
1471-2415
Abstract
Abstract Background To identify different response patterns to intravitreal dexamethasone implants (IDI) in naïve and previously treated (PT) diabetic macular edema (DME) eyes in a real-life setting. Methods 342 IDI injections (203 DME eyes) were included. Number of IDI injections, percentage (%) of eyes with 1, 2, 3 and ≥ 4 injections, time to reinjections, visual acuity (VA), intraocular pressure (IOP) and central retinal thickness (CRT) were evaluated for naïve and PT DME eyes over 24 months. Results Mean number of injections was significantly lower in naïve vs PT DME eyes (1.40 ± 0.9 vs 1.82 ± 0.9, p