학술논문
Sub-millisecond conformational dynamics of the A2A adenosine receptor revealed by single-molecule FRET
Document Type
article
Author
Ivan Maslov; Oleksandr Volkov; Polina Khorn; Philipp Orekhov; Anastasiia Gusach; Pavel Kuzmichev; Andrey Gerasimov; Aleksandra Luginina; Quinten Coucke; Andrey Bogorodskiy; Valentin Gordeliy; Simon Wanninger; Anders Barth; Alexey Mishin; Johan Hofkens; Vadim Cherezov; Thomas Gensch; Jelle Hendrix; Valentin Borshchevskiy
Source
Communications Biology, Vol 6, Iss 1, Pp 1-15 (2023)
Subject
Language
English
ISSN
2399-3642
Abstract
Single-molecule FRET experiments with human A2A adenosine receptor in its apo and agonist-bound states in lipid nanodiscs provide insights into its conformational dynamics and activation.