학술논문
A unique Pd-catalysed Heck arylation as a remote trigger for cyclopropane selective ring-opening
Document Type
article
Source
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Subject
Language
English
ISSN
2041-1723
Abstract
Functionalizing multiple, distant sites across a molecule is a challenge. Here the authors report a remote functionalization strategy, whereby an initial Heck reaction leads to chain-walking of palladium across a molecule, ring-opening cyclopropanes while retaining the stereochemistry in the product.