학술논문
Comparing Robotic-Assisted to Open Radical Cystectomy in the Management of Non-Muscle-Invasive Bladder Cancer: A Propensity Score Matched-Pair Analysis
Document Type
article
Author
Etienne Courboin; Romain Mathieu; Valentina Panetta; Georges Mjaess; Romain Diamand; Gregory Verhoest; Mathieu Roumiguié; Anne Sophie Bajeot; Francesco Soria; Chiara Lonati; Claudio Simeone; Giuseppe Simone; Umberto Anceschi; Paolo Umari; Ashwin Sridhar; John Kelly; Laura S. Mertens; Rafael Sanchez-Salas; Anna Colomer; Maria Angela Cerruto; Alessandro Antonelli; Wojciech Krajewski; Thierry Quackels; Alexandre Peltier; Francesco Montorsi; Alberto Briganti; Jeremy Y. C. Teoh; Benjamin Pradere; Marco Moschini; Thierry Roumeguère; Simone Albisinni
Source
Cancers, Vol 15, Iss 19, p 4732 (2023)
Subject
Language
English
ISSN
2072-6694
Abstract
Background: For non-muscle-invasive bladder cancer (NMIBC) requiring radical surgery, limited data are available comparing robotic-assisted radical cystectomy with intracorporeal urinary diversion (iRARC) to open radical cystectomy (ORC). The objective of this study was to compare the two surgical techniques. Methods: A multicentric cohort of 593 patients with NMIBC undergoing iRARC or ORC between 2015 and 2020 was prospectively gathered. Perioperative and pathologic outcomes were compared. Results: A total of 143 patients operated on via iRARC were matched to 143 ORC patients. Operative time was longer in the iRARC group (p = 0.034). Blood loss was higher in the ORC group (p < 0.001), with a consequent increased post-operative transfusion rate in the ORC group (p = 0.003). Length of stay was longer in the ORC group (p = 0.007). Post-operative complications did not differ significantly (all p > 0.05). DFS at 60 months was 55.9% in ORC and 75.2% in iRARC with a statistically significant difference (p = 0.033) found in the univariate analysis. Conclusion: We found that iRARC for patients with NMIBC is safe, associated with a lower blood loss, a lower transfusion rate and a shorter hospital stay compared to ORC. Complication rates were similar. No significant differences in survival analyses emerged across the two techniques.