학술논문
An integrated multi-omics analysis of sleep-disordered breathing traits implicates P2XR4 purinergic signaling
Document Type
article
Author
Nuzulul Kurniansyah; Danielle A. Wallace; Ying Zhang; Bing Yu; Brian Cade; Heming Wang; Heather M. Ochs-Balcom; Alexander P. Reiner; Alberto R. Ramos; Joshua D. Smith; Jianwen Cai; Martha Daviglus; Phyllis C. Zee; Robert Kaplan; Charles Kooperberg; Stephen S. Rich; Jerome I. Rotter; Sina A. Gharib; Susan Redline; Tamar Sofer
Source
Communications Biology, Vol 6, Iss 1, Pp 1-11 (2023)
Subject
Language
English
ISSN
2399-3642
Abstract
An integrated multi-omics analysis identifies an association chain among sleep-disordered breathing (SDB) traits, gene expression in circulating leukocytes, and serum metabolites, and supports a mechanistic role for P2XR4 purinergic signaling in SDB.