학술논문

Potential Refinement of Recurrence Score by pSTAT3 Status
Document Type
article
Source
Genes, Vol 13, Iss 3, p 438 (2022)
Subject
early breast cancer
recurrence score
oncotype
pSTAT3
prognosis
Genetics
QH426-470
Language
English
ISSN
2073-4425
Abstract
The likelihood of recurrence in breast cancer patients with hormone receptor-positive (HR-positive) tumors is influenced by clinical, histopathological, and molecular features. Recent studies suggested that activated STAT3 (pSTAT3) might serve as a biomarker of outcome in breast cancer patients. In the present work, we have analyzed the added value of pSTAT3 to OncotypeDx Recurrence Score (RS) in patient prognostication. We have found that patients with low RS (