학술논문
Inhibition of lung microbiota-derived proapoptotic peptides ameliorates acute exacerbation of pulmonary fibrosis
Document Type
article
Author
Corina N. D’Alessandro-Gabazza; Taro Yasuma; Tetsu Kobayashi; Masaaki Toda; Ahmed M. Abdel-Hamid; Hajime Fujimoto; Osamu Hataji; Hiroki Nakahara; Atsuro Takeshita; Kota Nishihama; Tomohito Okano; Haruko Saiki; Yuko Okano; Atsushi Tomaru; Valeria Fridman D’Alessandro; Miyako Shiraishi; Akira Mizoguchi; Ryoichi Ono; Junpei Ohtsuka; Masayuki Fukumura; Tetsuya Nosaka; Xuenan Mi; Diwakar Shukla; Kensuke Kataoka; Yasuhiro Kondoh; Masaki Hirose; Toru Arai; Yoshikazu Inoue; Yutaka Yano; Roderick I. Mackie; Isaac Cann; Esteban C. Gabazza
Source
Nature Communications, Vol 13, Iss 1, Pp 1-23 (2022)
Subject
Language
English
ISSN
2041-1723
Abstract
Here, the authors show that treatment with a monoclonal neutralizing antibody against the lung microbiota-derived proapoptotic peptide corisin ameliorates acute exacerbation of pulmonary fibrosis and severity of endotoxin-induced acute lung injury in mice.