학술논문
Reproductive fitness and genetic risk of psychiatric disorders in the general population
Document Type
article
Author
Niamh Mullins; Andrés Ingason; Heather Porter; Jack Euesden; Alexandra Gillett; Sigurgeir Ólafsson; Daniel F. Gudbjartsson; Cathryn M. Lewis; Engilbert Sigurdsson; Evald Saemundsen; Ólafur Ó Gudmundsson; Michael L. Frigge; Augustine Kong; Agnar Helgason; G. Bragi Walters; Omar Gustafsson; Hreinn Stefansson; Kari Stefansson
Source
Nature Communications, Vol 8, Iss 1, Pp 1-6 (2017)
Subject
Language
English
ISSN
2041-1723
Abstract
Why genetic variants that confer risk for psychiatric disorders persist in the genome is an evolutionary conundrum. Here, Mullinset al. report association of polygenic risk for autism with having fewer children and polygenic risk for ADHD with higher reproductive fitness.