학술논문
Integrated genomic analysis reveals mutated ELF3 as a potential gallbladder cancer vaccine candidate
Document Type
article
Author
Akhilesh Pandey; Eric W. Stawiski; Steffen Durinck; Harsha Gowda; Leonard D. Goldstein; Mustafa A. Barbhuiya; Markus S. Schröder; Sreelakshmi K. Sreenivasamurthy; Sun-Whe Kim; Sameer Phalke; Kushal Suryamohan; Kayla Lee; Papia Chakraborty; Vasumathi Kode; Xiaoshan Shi; Aditi Chatterjee; Keshava Datta; Aafaque A. Khan; Tejaswini Subbannayya; Jing Wang; Subhra Chaudhuri; Sanjiv Gupta; Braj Raj Shrivastav; Bijay S. Jaiswal; Satish S. Poojary; Shushruta Bhunia; Patricia Garcia; Carolina Bizama; Lorena Rosa; Wooil Kwon; Hongbeom Kim; Youngmin Han; Thakur Deen Yadav; Vedam L. Ramprasad; Amitabha Chaudhuri; Zora Modrusan; Juan Carlos Roa; Pramod Kumar Tiwari; Jin-Young Jang; Somasekar Seshagiri
Source
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Subject
Language
English
ISSN
2041-1723
Abstract
Gallbladder cancer incidence shows characteristic geographic patterns. Here the authors perform a genomic analysis of gallbladder cancers in patients from countries with high incidence (South Korea, India and Chile) and identify ELF3 and other significantly mutated genes not previously associated with gallbladder cancer.