학술논문
A spatially resolved brain region- and cell type-specific isoform atlas of the postnatal mouse brain
Document Type
article
Author
Anoushka Joglekar; Andrey Prjibelski; Ahmed Mahfouz; Paul Collier; Susan Lin; Anna Katharina Schlusche; Jordan Marrocco; Stephen R. Williams; Bettina Haase; Ashley Hayes; Jennifer G. Chew; Neil I. Weisenfeld; Man Ying Wong; Alexander N. Stein; Simon A. Hardwick; Toby Hunt; Qi Wang; Christoph Dieterich; Zachary Bent; Olivier Fedrigo; Steven A. Sloan; Davide Risso; Erich D. Jarvis; Paul Flicek; Wenjie Luo; Geoffrey S. Pitt; Adam Frankish; August B. Smit; M. Elizabeth Ross; Hagen U. Tilgner
Source
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Subject
Language
English
ISSN
2041-1723
Abstract
Alternative RNA splicing varies across the brain. Its mapping at single cell resolution is unclear. Here, the authors provide a spatial and single-cell splicing atlas reporting brain region- and cell type-specific expression of different isoforms in the postnatal mouse brain.