학술논문
Impact of dialysis modality on morbimortality of kidney transplant recipients after allograft failure. Analysis in the presence of competing events
Document Type
article
Author
Sandra Beltrán Catalán; Asunción Sancho Calabuig; Pablo Molina; Belén Vizcaíno Castillo; Eva Gavela Martínez; Julia Kanter Berga; Mercedes González Moya; Luis Manuel Pallardó Mateu; C. Gómez Roldán; A. Ortega Cerrato; M.D. Albero; J. Pérez-Contreras; E. Muñoz de Bustillo; J.M. Graña; A. Seores; A. Arlandis; C. Hernaiz; E. Bosque; V. Mascarós; C. Climent; M. Lanuza; A. Martínez; M. González; J.M. Escobedo; M. Montomoli; M. Giménez; A. Soldevila; R. Devesa; J.C. Alonso; S. Beltrán Catalán; B. Vizcaíno Castillo; E. Torregrosa; I. Millán; S. Ros; V. Ramos; B. Diez; D. Manzano; V. Andronic
Source
Nefrología (English Edition), Vol 41, Iss 2, Pp 200-209 (2021)
Subject
Language
English
ISSN
2013-2514
Abstract
Background and objective: The number of patients who start dialysis due to graft failure increases every day. The best dialysis modality for this type of patient is not well defined and most patients are referred to HD. The objective of our study is to evaluate the impact of the dialysis modality on morbidity and mortality in transplant patients who start dialysis after graft failure. Material and methods: A multicentre retrospective observation and cohort study was performed to compare the evolution of patients who started dialysis after graft failure from January 2000 to December 2013. One group started on PD and the other on HD. The patients were followed until the change of dialysis technique, retransplantation or death. Anthropometric data, comorbidity, estimated glomerular filtration rate (eGFR) at start of dialysis, the presence of an optimal access for dialysis, the appearance of graft intolerance and retransplantation were analyzed. We studied the causes for the first 10 hospital admissions after starting dialysis. For the statistical analysis, the presence of competitive events that hindered the observation of the event of interest, death or hospital admission was analyzed. Results: 175 patients were included, 86 in DP and 89 in HD. The patients who started PD were younger, had less comorbidity and started dialysis with lower eGFR than those on HD. The mean follow-up was 34 ± 33 months, with a median of 24 months (IQR 7–50 months), Patients on HD had longer follow-up than patients on PD (35 vs. 18 months, p =