학술논문

Modifiable factors associated with low bone mineral content in underprivileged premenarchal Indian girls
Document Type
research-article
Source
Journal of Pediatric Endocrinology and Metabolism. 24(11-12):975-981
Subject
BMC Z-scores
Indian
low bone mass
modifiable factors
premenarchal girls
underprivileged
Original Articles
Language
English
ISSN
2191-0251
0334-018X
Abstract
Low adolescent peak bone mass is associated with bone problems in adulthood. Our aim was to assess underprivileged premenarchal Indian girls for low bone mineral content and to study the influence of anthropometric, lifestyle factors on bone health. Data on anthropometry, diet, lifestyle, total body bone mineral content (TBBMC), bone area, bone mineral density, and biochemical parameters [parathyroid hormone, vitamin D (25OH-D), calcium, and zinc] were assessed in 214 premenarchal girls (8–12 years). Compared with the Indian reference database, 15.6% girls had TBBMC for age Z-scores below –2 and 37.5% had Z-scores between –2 and –1. The TBBMC for total body bone area Z-scores were below –2 for one fifth of girls, indicating undermineralized bones. Mean rate of increase in TBBMC with age and Tanner stage was lower in our study population (11.6% and 20.7%, respectively) than reference database (14.2% and 33.4%, respectively). Low weight, 25OH-D, and intake of protein, calcium, and zinc adversely affected TBBMC (p