부산대학교 도서관

Nanotechnology can solve many biomedical problems and cause transformation in the field of health and pharmaceuticals. The use of this technology in removing pathogenic bacteria is of great interest. The introduction of a strong antibacterial agent is very important to control pathogenic bacteria, especially strains resistant to antibiotics. The aim of this research was to synthesize silver nanoparticles (AgNPs) with the help of Abelmoschus esculentus aqueous extract and investigate its antibacterial properties against oral pathogens. Our study examined the ability of AgNPs to inhibit the dental bacterial growth and anti-adherence in vitro. The biosynthesized AgNPs@Abelmoschus esculentus were characterized by FT-IR, UV–Vis, and SEM tests. The physical and chemical investigation of the synthesized AgNPs showed that the particles were produced in nano dimensions, spherical shape, and without any impurities. In antibacterial test, the 8 µg/mL exhibited the lowest minimum inhibitory concentrations (MICs) against Porphyromonas gingivalis and Streptococcus mutans (MIC = 8 µg/mL). In vitro adherence of S. mutans was significantly prevented by AgNPs@Abelmoschus esculentus (MIC = 8–16 µg/mL). According to the results, the AgNPs@Abelmoschus esculentus may be good candidates for the oral hygiene agents to prevent periodontopathic conditions and dental caries.