학술논문
Pharmacology of Huperzine A, an Alkaloid Isolated from Huperzine Serrata, a Novel Cognition Enhancer with Dual Cholinergic and NMDA Action. Implications in Schizophrenia and Dementia
Document Type
research-article
Author
Source
Journal of Complementary and Integrative Medicine. 4(1)
Subject
Language
English
ISSN
1553-3840
Abstract
Recently, there has been an escalating interest in exploring novel pharmacological approaches in Alzheimer Dementia and Schizophrenia. We reviewed the pharmacology of Huperzine A, an alkaloid isolated from Huperzia Serrata. The dual action of Huperzine in inhibiting cholinesterase activity and modulating the excitatory amino acid neurotransmitter NMDA (N-methyl-D-aspartic acid) makes the compound highly appealing as target in pharmaceutical development as a cognitive enhancer agent.