학술논문

Application of a diagnosis flow draft based on appearance impression for detection of vulvar disease
Document Type
research-article
Source
Diagnosis. 11(2):151-163
Subject
vulvar disease
ternimology
vulvar intraepithelial neoplasia
vulvar Paget’s disease
overall diagnostic value
diagnosis flow draft
Language
English
ISSN
2194-802X
Abstract
Objectives The aims of this retrospective study were to evaluate the clinical applicability of the latest International Society for the Study of Vulvovaginal Disease (ISSVD) and International Federation for Cervical Pathology and Colposcopy (IFCPC) terminology for vulvar diseases, and to explore a new evaluation flow to optimize decision-making on diagnosis. Methods A total of 1,068 patients with 5,340 qualified vulvar images were evaluated by observers using 2011 ISSVD and 2011 IFCPC terminology systems. The sensitivity, specificity, positive predictive value, negative predictive value, Youden Index and Overall Diagnostic Value (ODV) were calculated for each finding in the two systems. Then the disease diagnosis order and a diagnosis flow draft (DFD) were obtained. Results A total of 15 kinds of vulvar diseases were diagnosed. The proportion of patients accompanied with cervical or vaginal intraepithelial neoplasia was highest (83.3 %) in vulvar Paget’s disease group (p Conclusions Based on the findings in ISSVD and IFCPC terminology systems, we explored a DFD for observers with different experience on the detection of vulvar disease.