학술논문
超选择性前列腺动脉栓塞术治疗良性前列腺增生临床初探 / Pilot study of super-selective prostatic arterial embolization in the treatment of benign prostatic hyperplasia
Document Type
Academic Journal
Author
曹广劭; 刘建文; 刘玉岩; 刘瑞青; 张强; 李陆鹏; 刘健; 李辉; 曹会存; 李天晓; CAO Guang-shao; LIU Jian-wen; LIU Yu-yan; LIU Rui-qing; ZHANG Qiang; LI Lu-peng; LIU Jian; LI Hui; CAO Hui-cun; LI Tian-xiao
Source
影像诊断与介入放射学 / Diagnostic Imaging & Interventional Radiology. 26(2):130-135
Subject
Language
Chinese
ISSN
1005-8001
Abstract
目的 评估超选择性前列腺动脉栓塞术治疗症状性良性前列腺增生的初步结果,为全面临床应用提供经验.方法 2014年12月～2016年12月,11例良性前列腺增生患者行超选择性前列腺动脉栓塞术治疗,栓塞材料采用Embosphere微球(40～120 μm、100～300 μm)及明胶海绵颗粒(350～560 μm).随访3～24个月,并分别于栓塞前及栓塞术后1、3和6个月复查,比较治疗前后患者的临床症状、术后反应及并发症情况.结果 11例栓塞技术均获得成功,技术成功率为100％,双侧栓塞10例,单侧栓塞1例,随访6个月,9例临床症状术后1、3和6个月较术前均有明显改善,临床有效率为81.8％(9/11);1例患者出现严重栓塞并发症,表现为泌尿系感染、大小便功能及性功能障碍.结论 大量文献及本组研究显示超选择性前列腺动脉栓塞术治疗良性前列腺增生安全、有效,在药物治疗无效、不适合或拒绝外科手术的患者中有较好的应用前景,但应注意把握适应证、规范操作.
Objective To evaluate the preliminary result of super-selective prostatic arterial embolization (PAE) for the treatment of benign prostatic hyperplasia (BPH) with lower urinary tract symptoms.Methods From December 2014 to December 2015,11 patients with BPH underwent super-selective PAE treatment with Embosphere microspheres (40-120 μm,100-300 μm) and gelfoam (350-560 μm).Clinical symptoms,postoperative reaction,and complications were used to assess the outcome before PAE,1 month,3 months,and 6 months after PAE.Results Bilateral (10) and unilateral (1) PAE was technically successful in all 11 patients.At 3-24 month follow-up,the symptoms improved significantly 1 month,3 months,and 6 months after operation in 9 patients with 81.8％ clinical success rate.Severe postoperative complications were observed in 1 patient,presenting as urinary tract infection,bladder and bowel dysfunction,and sexual dysfunction.Conclusion PAE is safe and effective in the management of patients with lower urinary tract symptoms of BPH,when medical therapy has failed and surgery or transurethral prostatic resection is not possible.
Objective To evaluate the preliminary result of super-selective prostatic arterial embolization (PAE) for the treatment of benign prostatic hyperplasia (BPH) with lower urinary tract symptoms.Methods From December 2014 to December 2015,11 patients with BPH underwent super-selective PAE treatment with Embosphere microspheres (40-120 μm,100-300 μm) and gelfoam (350-560 μm).Clinical symptoms,postoperative reaction,and complications were used to assess the outcome before PAE,1 month,3 months,and 6 months after PAE.Results Bilateral (10) and unilateral (1) PAE was technically successful in all 11 patients.At 3-24 month follow-up,the symptoms improved significantly 1 month,3 months,and 6 months after operation in 9 patients with 81.8％ clinical success rate.Severe postoperative complications were observed in 1 patient,presenting as urinary tract infection,bladder and bowel dysfunction,and sexual dysfunction.Conclusion PAE is safe and effective in the management of patients with lower urinary tract symptoms of BPH,when medical therapy has failed and surgery or transurethral prostatic resection is not possible.