학술논문
自拟辛夷通窍液在慢性鼻窦炎患者鼻内镜术后的应用价值 / Application Value of Self-made Xinyi Tongqiao Liquid in Patients with Chronic Sinusitis after Nasal Endoscopic Surgery
Document Type
Academic Journal
Author
Source
中国药物经济学 / China Journal of Pharmaceutical Economics. 18(12):53-56
Subject
Language
Chinese
ISSN
1673-5846
Abstract
目的 探讨自拟辛夷通窍液对慢性鼻窦炎(CRS)患者鼻内镜术后鼻内镜评分、鼻窦 CT 评分及鼻黏膜纤毛运动功能的影响.方法 选取2020 年3 月至2022 年3 月泰安市妇幼保健院收治的 108 例CRS患者作为研究对象,按随机数字表法分为观察组(n=54)及对照组(n=54).两组均行鼻内镜手术治疗,对照组术后给予高渗盐水鼻腔冲洗,观察组在对照组基础上给予自拟辛夷通窍液冲洗治疗.比较两组治疗有效率,术前、术后 6 周、术后 12 周L-K评分、L-M评分、鼻黏膜纤毛运动功能[纤毛传输时间(MTT)、纤毛传输速率(MTR)],并发症发生情况.结果 观察组治疗有效率高于对照组(P＜0.05).术后6 周、术后12 周,两组L-K评分、L-M评分、MTT降低(P＜0.05),且观察组低于对照组(P＜0.05);两组MTR升高(P＜0.05),且观察组高于对照组(P＜0.05).观察组术后并发症发生率低于对照组(P＜0.05).结论 CRS患者鼻内镜术后应用自拟辛夷通窍液冲洗治疗的临床疗效显著,可促进鼻黏膜纤毛运动功能恢复,降低术后并发症发生风险.
Objective To explore the effects of self-made Xinyi Tongqiao Fluid on nasal endoscopic score,sinus CT score and nasal mucociliary motor function in patients with chronic sinusitis(CRS)after nasal endoscopic surgery.Methods A total of 108 patients with CRS admitted to Tai'an Maternal and Child Health Hospital from March 2020 to March 2022 were selected as the study objects and divided into observation group(n=54)and control group(n=54)according to random number table method.The two groups were treated with nasal endoscopic surgery,the control group was given hypertonic saline nasal irrigation after operation,and the observation group was given self-designed Xinyi orifice liquid irrigation on the basis of the control group.The effective rate of treatment,and L-K score,L-M score,nasal mucociliary motor function[mucociliary transport time(MTT),mucociliary transport rate(MTR)]before surgery and at 6 weeks and 12 weeks after surgery,and occurrence of complications were compared between the two groups.Results The effective rate of the observation group was higher than that of the control group(P＜0.05).At 6 weeks and 12 weeks after surgery,L-K score,L-M score and MTT of two groups were decreased(P＜0.05),and the observation group was lower than the control group(P＜0.05);MTR of both groups was increased(P＜0.05),and observation group was higher than control group(P＜0.05).The incidence of postoperative complications in observation group was lower than that in control group(P＜0.05).Conclusion Self-made Xinyi Tongqiao liquid for irrigation of patients with CRS after nasal endoscopic surgery has significant clinical efficacy,and it can promote the recovery of postoperative nasal mucociliary motor function and reduce the risk of postoperative complications.
Objective To explore the effects of self-made Xinyi Tongqiao Fluid on nasal endoscopic score,sinus CT score and nasal mucociliary motor function in patients with chronic sinusitis(CRS)after nasal endoscopic surgery.Methods A total of 108 patients with CRS admitted to Tai'an Maternal and Child Health Hospital from March 2020 to March 2022 were selected as the study objects and divided into observation group(n=54)and control group(n=54)according to random number table method.The two groups were treated with nasal endoscopic surgery,the control group was given hypertonic saline nasal irrigation after operation,and the observation group was given self-designed Xinyi orifice liquid irrigation on the basis of the control group.The effective rate of treatment,and L-K score,L-M score,nasal mucociliary motor function[mucociliary transport time(MTT),mucociliary transport rate(MTR)]before surgery and at 6 weeks and 12 weeks after surgery,and occurrence of complications were compared between the two groups.Results The effective rate of the observation group was higher than that of the control group(P＜0.05).At 6 weeks and 12 weeks after surgery,L-K score,L-M score and MTT of two groups were decreased(P＜0.05),and the observation group was lower than the control group(P＜0.05);MTR of both groups was increased(P＜0.05),and observation group was higher than control group(P＜0.05).The incidence of postoperative complications in observation group was lower than that in control group(P＜0.05).Conclusion Self-made Xinyi Tongqiao liquid for irrigation of patients with CRS after nasal endoscopic surgery has significant clinical efficacy,and it can promote the recovery of postoperative nasal mucociliary motor function and reduce the risk of postoperative complications.