학술논문
胃肠道神经内分泌肿瘤的内镜误诊体会 / Experience of endoscopic diagnosis and treatment for gastrointestinal neuroendocriue tumor
Document Type
Academic Journal
Author
邓万银; 梁玮; 何利平; 郑金辉; 郑晓玲; 杨士杰; Wan-yin Deng; Wei Liang; Li-ping He; Jin-hui Zheng; Xiao-ling Zheng; Shi-jie Yang
Source
中国内镜杂志. 22(12):85-89
Subject
Language
Chinese
ISSN
1007-1989
Abstract
目的：探讨胃肠神经内分泌肿瘤（GI-NETs）内镜诊治特点，减少误诊。方法收集2012年1月-2014年11月该院内镜诊断的84例神经内分泌肿瘤（NET），回顾性分析其白光内镜、超声内镜（EUS）、组织病理学及治疗后情况等特点，总结其中误诊病例特点。结果经内镜诊断NET 84例，最终经病理证实为NET 72例，12例内镜误诊为NET，误诊率达14.3%，12例分别为慢性炎症5例，异位胰腺2例，布氏腺增生1例，大肠增生性息肉1例，大肠静脉型血管瘤1例，大肠平滑肌瘤1例，转移性鳞癌1例。8例行EUS检查，均提示病灶来源黏膜下层，6例为低回声，1例偏高回声（布氏腺增生），1例混合回声（静脉型血管瘤）。结论 GI-NETs在内镜下有一定的特征性，但有部分病例表现可类似，经过更为细致的观察和必要的活检可增加诊断的准确率。
Objective To study the characteristics of endoscopic diagnosis and treatment for gastrointestinal neuroendocriue tumor (GI-NETs).Methods We retrospectively collected the clinical data of 84 patients with endoscopic confirmed GI-NETs from January 2012 to November 2014, including white light, endoscopic ultrasonography, histopathology and post-treatment condition.Results Endoscopic diagnosis for NET were 84 cases, but ifnally conifrmed by pathology were 72 cases, the misdiagnosis rate was 14.3%. Of the 12 misdiagnosed cases, 5 cases were chronic inlfammation, ectopic pancreas in 2 cases, and 5 cases of hyperplasia of Brunner's glands, colorectal hyperplastic polyps, colorectal venous hemangioma, colorectal leiomyoma, metastatic squamous carcinoma respectively. Of 8 cases with EUS, all lesions derived from the submucosal layer, and 6 cases of low echo, and 2 cases of high echo (Brunner's glands) and mixed echo (venous hemangioma) respectively.Conclusions GI-NETs,which possess certain characteristics under endoscopy, may be similar with other digestive diseases, while it can increase the diagnosis accuracy by more careful observation and necessary biopsy.
Objective To study the characteristics of endoscopic diagnosis and treatment for gastrointestinal neuroendocriue tumor (GI-NETs).Methods We retrospectively collected the clinical data of 84 patients with endoscopic confirmed GI-NETs from January 2012 to November 2014, including white light, endoscopic ultrasonography, histopathology and post-treatment condition.Results Endoscopic diagnosis for NET were 84 cases, but ifnally conifrmed by pathology were 72 cases, the misdiagnosis rate was 14.3%. Of the 12 misdiagnosed cases, 5 cases were chronic inlfammation, ectopic pancreas in 2 cases, and 5 cases of hyperplasia of Brunner's glands, colorectal hyperplastic polyps, colorectal venous hemangioma, colorectal leiomyoma, metastatic squamous carcinoma respectively. Of 8 cases with EUS, all lesions derived from the submucosal layer, and 6 cases of low echo, and 2 cases of high echo (Brunner's glands) and mixed echo (venous hemangioma) respectively.Conclusions GI-NETs,which possess certain characteristics under endoscopy, may be similar with other digestive diseases, while it can increase the diagnosis accuracy by more careful observation and necessary biopsy.