학술논문
红细胞Rh血型相容性输血临床意义与经济性分析 / Clinical Significance and Economic Analysis of Erythrocyte Rh Blood Group Compatible Transfusion
Document Type
Academic Journal
Author
Source
临床输血与检验 / Journal of Clinical Transfusion and Laboratory Medicine. 25(6):783-788
Subject
Language
Chinese
ISSN
1671-2587
Abstract
目的 分析我院开展RhD,C,c,E,e抗原相容性输血的临床意义与经济性,为以后全面推广和普及Rh血型相容性输血以及卫生行政部门决策提供科学依据.方法 我们筛查并鉴定了Rh相容性输血组和对照组之间的意外抗体的产生情况.分析了Rh分型前后两年患者的住院时长和输血相关费用.结果 献血者红细胞的Rh抗原表型与患者的Rh抗原表型匹配度可高达92.43%.住院患者的意外抗体阳性率为1.72%(186/10 786),Rh血型系统抗体的检出率为43.30%,抗-Mia抗体的检出率为20.98%.接受Rh相容性输血的患者未产生新的Rh血型系统的抗体.Rh分型后,患者的次均住院时长和红细胞费用均有轻微降低.结论 Rh相容性输血可以显著减少新的意外抗体的产生.Rh相容性输血导致的输血相关检测费用的增长没有明显增加医疗费用.Rh相容性输血是值得推广和普及的.
Objective To analyze the clinical significance and economic analysis of RhD,C,c,E,e antigen compatible blood transfusion in our hospital,and provide scientific basis for the comprehensive promotion and popularization of Rh compatible blood transfusion and the decision-making of health administrative departments in the future.Methods We screened and identified the production of unexpected antibodies between Rh compatible transfusion group and control group.The length of hospital stay(LOS)and the cost of transfusion-related testing were analyzed in the two years before and after Rh phenotyping.Results The Rh antigen compatibility between donors'red blood cells and patients was high enough to transfuse Rh matched red blood cells for 92.43%of patients.The total ratio of unexpected antibodies was 1.72%(186/10,786),the antibody frequency of Rh system was 43.30%,anti-Mia was 20.98%.There is no new development of Rh system antibodies after Rh compatible transfusion.After Rh phenotyping,the mean LOS and the cost of red blood cells were slightly decreased.Conclusion Rh compatible transfusion can significantly diminish new unexpected antibodies.The increased cost of transfusion-related testing due to Rh compatible transfusion did not significantly increase medical costs.Rh compatible blood transfusion is worth promoting and popularizing.
Objective To analyze the clinical significance and economic analysis of RhD,C,c,E,e antigen compatible blood transfusion in our hospital,and provide scientific basis for the comprehensive promotion and popularization of Rh compatible blood transfusion and the decision-making of health administrative departments in the future.Methods We screened and identified the production of unexpected antibodies between Rh compatible transfusion group and control group.The length of hospital stay(LOS)and the cost of transfusion-related testing were analyzed in the two years before and after Rh phenotyping.Results The Rh antigen compatibility between donors'red blood cells and patients was high enough to transfuse Rh matched red blood cells for 92.43%of patients.The total ratio of unexpected antibodies was 1.72%(186/10,786),the antibody frequency of Rh system was 43.30%,anti-Mia was 20.98%.There is no new development of Rh system antibodies after Rh compatible transfusion.After Rh phenotyping,the mean LOS and the cost of red blood cells were slightly decreased.Conclusion Rh compatible transfusion can significantly diminish new unexpected antibodies.The increased cost of transfusion-related testing due to Rh compatible transfusion did not significantly increase medical costs.Rh compatible blood transfusion is worth promoting and popularizing.