학술논문
青年人心周脂肪体积和体重指数与重度冠状动脉狭窄的关系 / Relationship Between Paracardial Adipose Tissue Volume, Body Mass Index and Severe Coronary Artery Stenosis in Young People
Document Type
Academic Journal
Author
廖琦彬; 李彩英; 潘彤; 张丹; 寇晨光; 王岑; 贾芳莹; 郑彩瑞; LIAO Qi-bin; LI Cai-ying; PAN Tong; ZHANG Dan; KOU Chen-guang; WANG Cen; JIA Fang-ying; ZHENG Cai-rui
Source
中国循环杂志. 32(1):46-49
Subject
Language
Chinese
ISSN
1000-3614
Abstract
目的：采用256层螺旋计算机断层摄影术（CT）定量测量心周脂肪体积，评价心周脂肪体积及体重指数与青年人重度冠状动脉狭窄的关系。
方法：选取我院行CT冠状动脉造影（CTA）检查的45岁以下冠状动脉主支存在重度狭窄患者75例为病变组，75例冠状动脉正常者为对照组。分别记录两组患者的身高、体重，计算出体重指数，并将影像数据传至工作站，通过后处理软件测量心外膜脂肪体积、心包膜外脂肪体积及心周脂肪体积，并对心外膜脂肪体积、心包膜外脂肪体积及心周脂肪体积，三者间分别进行相关性分析。
结果：病变组的体重指数（28.169±2.203）kg/m2和心周脂肪体积（178.676±55.313）ml明显高于对照组[（24.960±3.041）kg/m2、（99.061±32.316）ml],差异均有统计学意义（P<0.05）。将病变组及对照组患者分别按照性别进一步分组后无论男性还是女性病变组的心周脂肪体积明显大于对照组（P<0.01）。心外膜脂肪体积与心包膜外脂肪体积、心外膜脂肪体积与心周脂肪体积、心包膜外脂肪体积与心周脂肪体积间均存在明显相关性(分别为r=0.837， P<0.001；r=0.971，P<0.001；r=0.944，P<0.001)。
结论：青年人心周脂肪体积及体重指数与重度冠状动脉狭窄显著相关。
Objective:To evaluate the relationship betweenparacardial adipose tissue (PAT) volume, body mass index (BMI) and severe coronary artery stenosis in young people by quantitative measurement of 256-slice spiral CT.
Methods: A total of 150 patients younger than 45 years and received coronary angiography (CAG) in our hospital were divided into 2 groups:Lesion group, the patients with severe main coronary branch stenosis and Control group, patients with normal coronary artery. n=75 in each group. The height, body weight and BMI were recorded in all patients;imaging data was uploaded to the workstation to calculate the volumes ofepicardiumadipose tissue (EAT) volume,pericardial outsideadipose tissue volume and PAT volume, the correlation among 3 parameters were analyzed respectively.
Results:Compared with Control group, Lesion group had increased BMI (28.169±2.203) kg/m2 vs (24.960±3.041) kg/m2 and PAT volume (178.676±3.041) ml vs (99.0616±3.041) ml, all P<0.05. Compared with Control group,no matter male or female, Lesion group had larger PAT volume, P<0.01.EAT volume was related to pericardial outside adipose tissue volume (r=0.837, P<0.001) and PAT volume (r=0.971, P<0.001);pericardial outside adipose tissue volume was related to PAT volume (r=0.944, P<0.001).
Conclusion:PAT volume and BMI were obviously correlated to severe coronary artery stenosis in young people.
方法：选取我院行CT冠状动脉造影（CTA）检查的45岁以下冠状动脉主支存在重度狭窄患者75例为病变组，75例冠状动脉正常者为对照组。分别记录两组患者的身高、体重，计算出体重指数，并将影像数据传至工作站，通过后处理软件测量心外膜脂肪体积、心包膜外脂肪体积及心周脂肪体积，并对心外膜脂肪体积、心包膜外脂肪体积及心周脂肪体积，三者间分别进行相关性分析。
结果：病变组的体重指数（28.169±2.203）kg/m2和心周脂肪体积（178.676±55.313）ml明显高于对照组[（24.960±3.041）kg/m2、（99.061±32.316）ml],差异均有统计学意义（P<0.05）。将病变组及对照组患者分别按照性别进一步分组后无论男性还是女性病变组的心周脂肪体积明显大于对照组（P<0.01）。心外膜脂肪体积与心包膜外脂肪体积、心外膜脂肪体积与心周脂肪体积、心包膜外脂肪体积与心周脂肪体积间均存在明显相关性(分别为r=0.837， P<0.001；r=0.971，P<0.001；r=0.944，P<0.001)。
结论：青年人心周脂肪体积及体重指数与重度冠状动脉狭窄显著相关。
Objective:To evaluate the relationship betweenparacardial adipose tissue (PAT) volume, body mass index (BMI) and severe coronary artery stenosis in young people by quantitative measurement of 256-slice spiral CT.
Methods: A total of 150 patients younger than 45 years and received coronary angiography (CAG) in our hospital were divided into 2 groups:Lesion group, the patients with severe main coronary branch stenosis and Control group, patients with normal coronary artery. n=75 in each group. The height, body weight and BMI were recorded in all patients;imaging data was uploaded to the workstation to calculate the volumes ofepicardiumadipose tissue (EAT) volume,pericardial outsideadipose tissue volume and PAT volume, the correlation among 3 parameters were analyzed respectively.
Results:Compared with Control group, Lesion group had increased BMI (28.169±2.203) kg/m2 vs (24.960±3.041) kg/m2 and PAT volume (178.676±3.041) ml vs (99.0616±3.041) ml, all P<0.05. Compared with Control group,no matter male or female, Lesion group had larger PAT volume, P<0.01.EAT volume was related to pericardial outside adipose tissue volume (r=0.837, P<0.001) and PAT volume (r=0.971, P<0.001);pericardial outside adipose tissue volume was related to PAT volume (r=0.944, P<0.001).
Conclusion:PAT volume and BMI were obviously correlated to severe coronary artery stenosis in young people.