학술논문

高血压合并糖尿病患者基于腹部CT指标的危险因素分析 / Analysis of risk factors in hypertension patients with diabetes mellitus based on abdominal computed tomography features
Document Type
Academic Journal
Source
东南大学学报(医学版) / Journal of Southeast University(Medical Science Edition). 36(6):887-891
Subject
高血压
糖尿病
危险因素
体层摄影术,X线计算机
hypertension
diabetes mellitus
risk factors
tomography
X-ray computed
Language
Chinese
ISSN
1671-6264
Abstract
目的:分析高血压合并糖尿病患者腹部CT的图像特征及其他相关指标,探讨高血压人群并发糖尿病的危险因素.方法:回顾性分析1962例在东南大学附属中大医院行腹部CT平扫的患者临床资料,分为正常对照组(n=858)、高血压组(n=732)、糖尿病组(n=128)及高血压合并糖尿病组(n=244).测量所有受检者腹部CT相关指标包括脂肪肝、胰/脾CT值、内脏脂肪(VAT)面积、皮下脂肪(SAT)面积、VAT/SAT面积值、腰大肌CT值及腹主动脉钙化评分.应用Logistic回归分析筛选高血压人群并发糖尿病的危险因素.结果:Logistic回归分析显示,脂肪肝、甘油三酯水平升高、高密度脂蛋白水平降低、高血压分级增高、腰围增大及腰大肌CT值减低是高血压人群发生糖尿病的危险因素.结论:脂肪肝、增高的高血压分级、肌肉脂肪浸润程度、腰围增大和血脂异常均会增加高血压患者糖尿病的发病率.
Objective:To analyze the image feature of abdominal CT and other related indicators , and to discuss clinical risk factors for developing diabetes mellitus in patients with hypertension .Methods:A retrospective review of 1962 patients undergoing abdominal CT scan was performed in Zhongda Hospital Affiliated Southeast University . The patients were divided into control group ( n=858 ) , hypertension group ( n =732 ) , diabetes mellitus group ( n=128 ) and hypertension with diabetes mellitus group ( n=244 ) .Abdominal CT parameters were evaluated , in-cluding fatty liver , CT attenuation ratio of pancreas to spleen , visceral fat tissue ( VAT) area, subcutaneous fat tis-sue area, VAT/SAT area ratio,lumbar muscle CT attenuation and abdominal aortic calcification .The risk factors for developing diabetes mellitus in hypertension patients were analyzed by Logistic regression analysis .Results:Lo-gistic regression analysis showed that fatty liver , increased triglyceride , decreased high density lipoprotein , high grade of hypertension , increased waist circumference , and the decreased psoas muscle CT attenuation were the risk factors for developing diabetes mellitus in hypertension patients .Conclusion:In hypertension patients , fatty liver, high grade hypertension , muscle fat infiltration , increased waist circumference and hyperlipidemia are the independ-ent risk factors for developing diabetes mellitus .