학술논문

Construction of nanoreactors on TiO2 nanotube arrays as a POCT device for sensitive colorimetric detection
Document Type
Academic Journal
Source
中国化学快报(英文版) / Chinese Chemical Letters. 34(5):389-392
Subject
Point-of-care testing
TiO2 nanotube arrays
Colorimetry
Alkaline phosphatase
Nano test tube
Language
Chinese
ISSN
1001-8417
Abstract
With increasing attention to personalized healthcare,miniaturized and easily implementable devices are desired for point-of-care testing(POCT).Herein,hydrophilic patterns were designed on freestanding TiO2 nanotube arrays(TiNTs)as nanoreactors for a naked-eye colorimetric assay.With a high aspect ratio,TiNTs can provide a long observation length combined with a limited volume.Moreover,by combining the photocatalytic property of TiO2 and spatiotemporal controllability of light,hydrophilic nanoreactors were fabricated with minimal volume,and thus the indicator and analyte are limited in a confined void by the hydrophobic surroundings,thus allowing a higher sensitivity for sensing.We believe the proposed sensing platform could provide a promising strategy in developing POCT devices for routine health mon-itoring.