학술논문

慢性阻塞性肺疾病患者吸入制剂依从性调查 / Investigation on adherence to inhaled medication among patients with chronic obstructive pulmonary disease
Document Type
Academic Journal
Source
临床肺科杂志 / Journal of Clinical Pulmonary Medicine. 22(4):658-661
Subject
慢性阻塞性肺疾病
吸入剂
依从性
chronic obstructive pulmonary diseases
inhaled medications
adherence
Language
Chinese
ISSN
1009-6663
Abstract
目的 调查慢性阻塞性肺疾病(慢阻肺)患者出院后使用吸入制剂的依从性情况及影响因素.方法 通过查询患者吸入剂处方信息结合电话随访问卷,对本院呼吸内科2013年1月-2015年6月收治的出院诊断为慢阻肺且医嘱长期使用吸入制剂的患者进行调查.结果 共收治了49例慢阻肺患者,纳入本研究的患者39例,其中46.2%(n=18)依从性好,53.8%(n=21例)依从性差.病程长短和急性发作次数(次/年)是影响吸入制剂依从性的相关因素.病程长(>10年),急性加重次数多(≥2次/年)的患者依从性差(P<0.05).患者依从性差的原因包括:缺乏对慢阻肺的认识,未及时复诊,遗忘配药,配药不便,觉得吸入制剂没效果,认为吸入制剂费用昂贵.结论 尽管患者在住院期间均进行过用药宣教,但结果提示收效并不理想.临床医生和药师应该采用积极的干预措施,提高患者长期规范用药依从性.
Objective To investigate the factors associated with adherence to inhaled medications among dis-charged patients with COPD. Methods Those patients with COPD discharged from respiratory ward and prescribed long-acting inhaled medications from January 2013 to June 2015 were investigated by prescription information and tel-ephone questionnaire. Results 39 patients included in the study from 49 hospitalized patients with COPD, 46. 2%(n=18) were with higher adherence while 53. 8% (n=21) were with lower adherence. The factors associated with adherence were course of disease and frequency of exacerbations. Longer course of disease ( >10 years) and higher frequency of exacerbations (≥2 per year) were associated with lower adherence (P<0. 05). Lower adherence was associated with lack of knowledge of COPD, delayed return visit, forgetting prescription, unavailable for prescription, considering inhaled medications ineffective or expensive. Conclusion Although all inpatients were repeatedly edu-cated, the results showed unsatisfactory. Physicians and pharmacists should intervene to improve adherence to inhaled medications.