학술논문
病程对Ⅱ型糖尿病患者不同部位皮肤厚度的影响 / Changes of Skin Thickness in Type Ⅱ Diabetes Mellitus Patients with Different Courses
Document Type
Academic Journal
Source
中国超声医学杂志 / Chinese Journal of Ultrasound in Medicine. 33(2):163-165
Subject
Language
Chinese
ISSN
1002-0101
Abstract
目的 观察病程对Ⅱ型糖尿病患者不同部位皮肤厚度的影响.方法 选取住院的Ⅱ型糖尿病患者346例,及非糖尿病对照组(C) 102例,按病程长短分为初发组(E) 84例、短病程组(S) 148例、长病程组(L) 114例.利用超声皮肤成像技术测量患者胸壁及下肢远端皮肤厚度,比较4组患者皮肤厚度差异及变化趋势.结果 不同病程的糖尿病E、S、L组与非糖尿病C组之间,皮肤厚度存在显著差异,差异有统计学意义(P＜0.05).检测部位不同,皮肤厚度随病程变化的趋势也不同,E、S、L组患者的胸壁皮肤均厚于非糖尿病C组(P＜0.05);而对于下肢远端,当病程超过1年时,糖尿病患者内踝区皮肤开始变薄,病程超过10年后,内外踝区皮肤均明显变薄(P＜0.05).结论 超声可用于无创性评估Ⅱ型糖尿病患者的皮肤厚度.胸壁处皮肤在患糖尿病后即开始增厚;而下肢远端皮肤则在病程超过10年时明显变薄.
Objective To observe the changes of skin thickness in type Ⅱ diabetes mellitus patients with different courses.Methods 346 patients with T2DM were recruited and divided into thre groups,84 patients in early stage (E:diabetes course≤1year),148 patients in short course (S:1year＜ diabetes course ≤10 years) and 114 patientsin long course (L:diabetes course＞ 10 years).102 healthy age-matched volunteers were recruited as the control.The chest and lower extremity skin thickness was measured by ultrasound,One-way analysis of variance was used to analyze the differences between the four groups.Results Significant differences in skin thickness was found among the E,S,L,C groups(P＜0.05).The thickness of chest wall's skin was increased in all diabetics(E,S,L groups) compared with healthy control.While when the history of diabetes over ten years,thickness of lower extremity skin was reduced (P＜0.05).Conclusions Ultrasound is a feasible method for measurement of T2DM skin thickness.The thickness of chest wall's skin begin to increased in all diabetics.Ten years seems to be the time when the lower extremity skin becomes noticeable thin among T2DM patients.
Objective To observe the changes of skin thickness in type Ⅱ diabetes mellitus patients with different courses.Methods 346 patients with T2DM were recruited and divided into thre groups,84 patients in early stage (E:diabetes course≤1year),148 patients in short course (S:1year＜ diabetes course ≤10 years) and 114 patientsin long course (L:diabetes course＞ 10 years).102 healthy age-matched volunteers were recruited as the control.The chest and lower extremity skin thickness was measured by ultrasound,One-way analysis of variance was used to analyze the differences between the four groups.Results Significant differences in skin thickness was found among the E,S,L,C groups(P＜0.05).The thickness of chest wall's skin was increased in all diabetics(E,S,L groups) compared with healthy control.While when the history of diabetes over ten years,thickness of lower extremity skin was reduced (P＜0.05).Conclusions Ultrasound is a feasible method for measurement of T2DM skin thickness.The thickness of chest wall's skin begin to increased in all diabetics.Ten years seems to be the time when the lower extremity skin becomes noticeable thin among T2DM patients.